earlier tonight I was listening to twiv from the 16th, and they also covered this weird Spike protein paper. I really appreciate your write up, because it took them about half an hour or to explain but the reason they were covering something for which they were scratching their heads as to why the experiment was done in the first place given that it had no relation to anything real life was because anti-vaxxers were latching on to it.
How do nonsense conclusions like this pass peer review? This isn't the first egregiously overstepping conclusion I've seen by far, but it's probably one of the worst.
You wrote, "Lastly, it just doesn’t seem possible for spike protein to be getting into the right place to do this. The mRNA and adenovirus-vector vaccines are all sent right into the muscle. They don’t go anywhere near the bone marrow and they don’t produce spike proteins in a way that it seems possible for those products to get into bone marrow or the thymus."
How about the non-US-approved vaccines, e. g. all the Chinese ones, that are either inactivated virus or protein subunit? I'm actually pretty sure neither one could introduce spike into the nucleus (where DNA replicates in mammalian cells) but you're the expert. Certainly spike can bind to the cell membrane, but does it pass the nuclear membrane?
You refer to a "protected compartment" (meaning the bone marrow), but at the cellular level the nucleus is also a protected compartment.
I think the key point is that infection introduces orders of magnitude more spike protein into a person's body than any vaccination, attached to actual virions.
earlier tonight I was listening to twiv from the 16th, and they also covered this weird Spike protein paper. I really appreciate your write up, because it took them about half an hour or to explain but the reason they were covering something for which they were scratching their heads as to why the experiment was done in the first place given that it had no relation to anything real life was because anti-vaxxers were latching on to it.
I am now going to disregard my own advice about MDPI and ask you, John, if you have any thoughts on this ostensible report of a case of vaccine-induced MIS-C: https://www.researchgate.net/publication/356384174_Autoantibody_Release_in_Children_after_Corona_Virus_mRNA_Vaccination_A_Risk_Factor_of_Multisystem_Inflammatory_Syndrome
How do nonsense conclusions like this pass peer review? This isn't the first egregiously overstepping conclusion I've seen by far, but it's probably one of the worst.
Another article was just published, also from an MDPI journal, raising concerns about COVID vaccination in pregnancy: https://mdpi-res.com/d_attachment/vaccines/vaccines-09-01351/article_deploy/vaccines-09-01351.pdf
At least a couple of the authors have been involved in antivax activity in Canada.
You wrote, "Lastly, it just doesn’t seem possible for spike protein to be getting into the right place to do this. The mRNA and adenovirus-vector vaccines are all sent right into the muscle. They don’t go anywhere near the bone marrow and they don’t produce spike proteins in a way that it seems possible for those products to get into bone marrow or the thymus."
How about the non-US-approved vaccines, e. g. all the Chinese ones, that are either inactivated virus or protein subunit? I'm actually pretty sure neither one could introduce spike into the nucleus (where DNA replicates in mammalian cells) but you're the expert. Certainly spike can bind to the cell membrane, but does it pass the nuclear membrane?
You refer to a "protected compartment" (meaning the bone marrow), but at the cellular level the nucleus is also a protected compartment.
I think the key point is that infection introduces orders of magnitude more spike protein into a person's body than any vaccination, attached to actual virions.